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(rel)-ML-SI3 is a small-molecule modulator of TRPML (mucolipin) ion channels used to probe TRPML1/2/3 function and autophagy in biochemical and cell-based research. It inhibits TRPML1 and TRPML3 while activating TRPML2, and is supplied at high purity for experimental use.
Modulates TRPML1, TRPML2, and TRPML3 activity in vitro.
Inhibits TRPML1 with IC50 ≈ 3.1 μM.
Activates TRPML2 with EC50 ≈ 3.3 μM.
Inhibits TRPML3 with IC50 ≈ 28.5 μM.
High purity suitable for biochemical and cellular assays.
Available as powder and as DMSO solution for screening.
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(rel)-ML-SI3 is a small-molecule TRPML1/3 inhibitor intended for preclinical and in vitro research. The compound is supplied as a white to off-white solid with high reported purity and is used as a pharmacological tool to study lysosomal calcium signaling, autophagy, and related cellular pathways.
High purity suitable for biochemical and cellular assays.
Solid form for convenient handling and storage.
Available in small-scale quantities for screening and optimization.
Applicable for studies of lysosomal function and autophagy-related mechanisms.
Molecular formula C23H31N3O3S and molecular weight 429.58 g·mol⁻¹ for reference.
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( )- -Tocopherol is a biologically active form of vitamin E which is a lipid-soluble antioxidant that protects cellular membranes from oxidative damage
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Vitamin K2 also known as menaquinone is a polyisoprenoid-substitutednbspnapthoquinone. Menaquinone-7 (MK-7) is a subtype of vitamin K2. It is found in animals soy protein fermented products and is primarily produced by bacteria.Vitamin K2 (MK-7)-(5 6 7 8-d4 2-methyl-d3) is a deuterated vitamin K2 wherein C-5 C-6 C-7 C-8 and 2-methyl protons are replaced by deuterium.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More